In Silco Molecular Modeling of Chalcone Based Aryloxyethylamines as Antihyperglycemic Agents
نویسندگان
چکیده
منابع مشابه
Tropical plant extracts as potential antihyperglycemic agents.
Preliminary investigations on 14 plant extracts (obtained by ethanolic and aqueous extraction) identified those having high antioxidant and a significant total phenolic content. Antihyperglycemic, α-amylase and α-glucosidase inhibition activities were also observed. A correlation between the antihyperglycemic activity, total phenolic content and antioxidant (DPPH scavenging) activity was establ...
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Deoxyribonucleic acid (DNA) is an important molecular target for anti-cancer agents due to its involvement in gene expression and protein synthesis which are fundamental steps in cell division and growth. A number of antineoplastic agents interfere with DNA and hence disturb the cell cycle. Compounds including planar aromatic rings are privileged scaffolds in binding to the DNA. This characteri...
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ژورنال
عنوان ژورنال: Medicinal Chemistry
سال: 2017
ISSN: 2161-0444
DOI: 10.4172/2161-0444.1000461